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Search Results for " kras degrader-1 "

6

Compounds

Cat No. Product Name Synonyms Targets
T79147 KRAS degrader-1
KRAS degrader-1 (compound 1) is a potent agent that selectively targets KRAS proteins for destruction via the autophagy-lysosomal degradation pathway [1].
T13844 PROTAC K-Ras Degrader-1 Ras , PROTACs
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
T77926 PROTAC KRAS G12C degrader-1 PROTACs
PROTAC KRAS G12C degrader-1, a cereblon-based degrader, promotes CRBN/KRAS G12C dimerization and facilitates the degradation of GFP-KRAS G12C in reporter cells [1].
T79148 PROTAC KRAS G12C degrader-3 Ras
PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].
T74439 PROTAC SOS1 degrader-1
PROTAC SOS1 degrader-1, a potent compound, demonstrates an effective degradation of PROTAC SOS1 with a DC50 value of 98.4 nM. It exhibits antiproliferative activity against cancer cells harboring diverse KRAS mutations a...
T74755 TUS-007
TUS-007, a modified CANDDY (Chemical knockdown with Affinity aNd Degradation DYnamics) molecule originally derived from a proteasome inhibitor, scarcely affects proteasome activity. It is a potent, orally active degrader...
TargetMol