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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79147 | KRAS degrader-1 | ||
KRAS degrader-1 (compound 1) is a potent agent that selectively targets KRAS proteins for destruction via the autophagy-lysosomal degradation pathway [1]. | |||
T13844 | PROTAC K-Ras Degrader-1 | Ras , PROTACs | |
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC. | |||
T77926 | PROTAC KRAS G12C degrader-1 | PROTACs | |
PROTAC KRAS G12C degrader-1, a cereblon-based degrader, promotes CRBN/KRAS G12C dimerization and facilitates the degradation of GFP-KRAS G12C in reporter cells [1]. | |||
T79148 | PROTAC KRAS G12C degrader-3 | Ras | |
PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1]. | |||
T74439 | PROTAC SOS1 degrader-1 | ||
PROTAC SOS1 degrader-1, a potent compound, demonstrates an effective degradation of PROTAC SOS1 with a DC50 value of 98.4 nM. It exhibits antiproliferative activity against cancer cells harboring diverse KRAS mutations a... | |||
T74755 | TUS-007 | ||
TUS-007, a modified CANDDY (Chemical knockdown with Affinity aNd Degradation DYnamics) molecule originally derived from a proteasome inhibitor, scarcely affects proteasome activity. It is a potent, orally active degrader... |